EFFECTS OF CYPERMETHRIN ON GROWTH, BIOCHEMICAL AND REPRODUCTIVE PARAMETERS IN MALE QUAILS (Coturnix japonica)

JUSTIN KOUAMO; SANDRINE PABAME MAYANG; FRANÇOIS KOUATCHO DJITIE; ABDOULMOUMINI MAMOUDOU

EFFECTS OF CYPERMETHRIN ON GROWTH, BIOCHEMICAL AND REPRODUCTIVE PARAMETERS IN MALE QUAILS (Coturnix japonica)

JUSTIN KOUAMO, SANDRINE PABAME MAYANG, FRANÇOIS KOUATCHO DJITIE, ABDOULMOUMINI MAMOUDOU

Resumen

This study aimed to determine the effects of cypermethrin insecticide on growth, biochemical and reproductive parameters in male Japanese quail
(Coturnix japonica). Seventy-two (72) male quails of equivalent body weights (185.96±1.74g) were divided into four groups of 18 birds each. Groups
received either 0, 130, 285, or 655 mg of cypermethrin/kg of feed for six weeks. Cypermethrin resulted in a significant decrease (p<0.05) in feed
intake, live body weight, and bodyweight gain compared to the control. Liver and kidney weight increased significantly (p<0.05). However, heart
weight decreased significantly compared with control. Histological structures of the liver and kidney demonstrated leucocytic infiltration, and in the
kidney, glomerulonephritis was present. Biochemically, serum levels of ALT, AST, creatinine, and urea significantly (p<0.05) reduced in all groups
receiving Cypermethrin compared to the control group. For reproductive parameters, Cypermethrin resulted in a significant (p<0.05) decrease in
testes weight, testosterone concentration, sperm cells concentration, and motility. At the testes level, it was observed degeneration of Sertoli cells,
incrementing the lumen of seminiferous tubes, and decreasing spermatogenesis. These results confirm the toxicity of Cypermethrin in male quail.

RESUMEN

Este estudio tuvo como objetivo determinar los efectos del insecticida cipermetrina sobre los parámetros de crecimiento, bioquímicos y reproductivos
de la codorniz japonesa macho (Coturnix japonica). Setenta y dos (72) codornices macho de pesos corporales equivalentes (185,96±1,74 g) se dividieron
en cuatro grupos de 18 aves cada uno. Los grupos recibieron 0, 130, 285 o 655 mg de cipermetrina/kg de alimento durante seis semanas. La
cipermetrina resultó en una disminución significativa (p <0.05) en la ingesta de alimento, el peso corporal vivo y la ganancia de peso corporal en
comparación con el control. El peso del hígado y los riñones aumentaron significativamente (p <0,05). Sin embargo, el peso del corazón disminuyó
significativamente en comparación con el control. Las estructuras histológicas del hígado y riñón demostraron infiltración leucocitaria, y en el riñón
además se observó glomerulonefritis. Bioquímicamente, los niveles séricos de ALT, AST, creatinina y urea se redujeron significativamente (p <0,05)
en todos los grupos que recibieron cipermetrina en comparación con el grupo de control. Para los parámetros reproductivos, la cipermetrina resultó
en una disminución significativa (p <0.05) en el peso de los testículos, la concentración de testosterona, la concentración de espermatozoides y la
motilidad. A nivel de los testículos, se observó degeneración de las células de Sertoli, aumento del lumen de los tubos seminíferos y disminución de
la espermatogénesis. Estos resultados confirman la toxicidad de la cipermetrina en la codorniz macho.

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